I think one of the following seems best.
Caprica:
-if you've got a decent super-crisis, now's the time to play it. Humans will be hard-pressed to stop it, and I can potentially sabotage (depending on what's negative).
-if not, you can draw top 2 crises and do one. If QVist made the right choice in leaving the one currently on top there, then ditching it seems like a good idea.
Cylon Fleet:
-move that centurion along. It will take 3 activations to win the game this way. But then if any of the crises are heavy raider activations, we win next turn. Of course, even better would be if your super-crisis activated heavy raiders in addition to whatever else you do.
There's also Human Fleet:
If you snatched an XO from Apollo he might not be able to get Zarek out of sick bay. That would be nice. And another damage on Galactica would be pretty great.
Looking over the Super Crises, there's only a couple there that wouldn't be worth it. So, unless you have one that's totally not worth it, I think that's my best suggestion. (by next turn, some of the humans might have gotten out of the brig...so it will be harder to get a failure on the crisis check.)