multiple scum-teams are always complicated
Mimes are a bit different...we can't kill them, but they also don't add a kill. our best bet is to win before them.
Let's see...with 12 players, 8 town...we need to lynch scum before it gets to 4 players (assuming we never lynch mimes, and they never get nk'd).
Assuming 1 lynch/1 nk each day, that gives us 4 days to win. (Day2=10 players, Day3=8 players, Day4=6 players, Day5=5 players, since mafia all were lynched)
If we lynch mimes once, then we can win at 3 players, so that's like a null-day, otherwise we need to hit mafia by Day 3.
Of course, if a mime is nk'd that changes everything, and so if we fail to lynch mafia on Day 3, but mafia nk's the mimes, then Day4 has 5 players and 2 mafia=lylo.
There's also the vig, the bomb, the jailkeeping, babysitter, and weak doctor...any of those can change number of town and/or mafia players alive on a given day. But failing any interesting night-activity, we have 3 days to hit scum, which is pretty normal. But they're only 1/6 of the players, which will make things tough.