These are some good cards. I like Black Powder, Distil, Ingredients, Chain Reaction, Aqua Vitae, Royal Archives, Sanctum, and the four Elements split pile and plan to include them in the alchemy set i am developing.
Chain Reaction may not cost enough - maybe $2P would be better?
Have you considered any other Horizontals? I made 11 Events, 5 Projects, and 4 Ways so far