Nomad camp / Peddler ? This is probably a terrible idea but it's fun to know that you can open with peddler. And maybe not that bad
You can already do that in Dark Ages games with Necropolis, and get yourself a Poor House too if you're lucky.
Now with Baker, you can get yourself any $2 card. If you're planning on picking up a TFB Squire seems like a good move.
You can open Nomad Camp/Border Village(/Death Cart/Ruins/Ruins)/Ruins, which will give your death cart a lot to work with, and I think 6 unique cards is the most that can be opened with barring multiplayer shenanigans. Nomad Camp/Death Cart/Squire or Hamlet is probably better though.
Speaking of shenanigans, opening with a $6 Doctor gives you a good chance of cleaning out your junk on turn 2, and you'll probably have more than $2 on your second turn with a thinner deck. Best case scenario, you can open $6/$5. Worst case scenario, you still get $2, you've already trashed one of your junk cards, and you can play the Doctor to try trash the others.