Here's a potential one - a 4-player game in which there's an engine deck to be made and the only Village is a vanilla Village. But the other components are not going to run out. I'd consider opening Remake/Village in some case like that.
This is the case I was thinking of. I've run into situations in 3-4 player games where the only village was Village and I didn't get enough of them to make the engine work.
