One could argue that the existence of the supernatural, such as Werewolf, Witch, etc; dictates that it must be set in some other fantasy world, similar to Middle Earth.
Is magic real?
This question got me thinking: what is a curse thematically? They seem to imply magic, but lots of non-magical stuff gives them out: Mountebanks, Jesters, Hideouts, etc.
Initially the idea was to have a hint of magic with no clear demonstration of it being real magic. I decided to make Alchemy anyway, it had pure fantasy things. Then when the main set was published, Witch was shown with magic despite me specifying otherwise, so so much for that. In the end the game is set in the medieval Europe of many stories, not just fairy tales but you know, Shakespeare plays and so on; it's mostly the real world, but with some magical stuff. People believed in ghost ships and there's a ghost ship, you know. Except Alchemy has some flat-out fantasy stuff, and then Nocturne has tons of it, it's Celtic fairy tales.
With magic not being clearly real, Witch and Mountebank are the same kind of thing. With actual magic, well Curses I guess are both magical and non-magical things that are in your way.
Sir Bailey had the second copy of Dominion, and took the name Castle Builder to heart, changing Curse to Rubble and having those attacks be siege weapons. I considered Rubble but stuck with Curse.