I wish I could dump all six votes into drawing both buys on Turn 5. It aggravates me so, and the dread build sup. In Turn 3, I'm thinking, "Well, it's rare that I won't get one of those cards next turn but that's not likely to happen. Or is it? Crap, what if it does?" And then when Turn 4 comes around, that fear is realized, and I know that those two cards are my buys.
I'd also vote for anything that loses those buys in turns 3 and 4. Basically, it's a combination of the Turn 5 blues and the Sea Hag blues. I *could* have had a critical card in turn 4, but my opponent's Sea Hag/Jester/whatever just took it out of commission until my next shuffle.
I didn't vote for the Familiar only because I don't play with it often enough. I recognize the pain in it, much like I recognize the pain of taking a stapler to the hand even though I've never had it happen.