Hmm, strongest for me would be: If you could start with 7 Coppers, 3 E/S and this card, which would you prefer?
I'm only counting up to Adventures, since I don't have any experience with Empires.
Champion is pretty darn strong, since you won't have to worry about terminal collision or being attacked ever again, so whatever you're trying to do, it will be way faster.
You won't have to spend any time buying Villages to create a smooth draw engine, just buy only drawers. Since you can always play any drawer, trashing is a bit less of an issue, you don't have to work as hard to get Village+drawer in the same hand.