I can see a ton of potential issues here. Firstly, Dragon's wording is pretty vague. So in a 2 player game, you're basically dividing the cards on the mat by 4. In 3 player, you're dividing by 6, and so on, right? Secondly, a lot of the time Dragon is really weak. You play Dragon, great, I get to trash a copper for free, thank you. Do that a total of four times, and finally you'll be getting +$1 from your Dragon plays. But if you can play several Dragons regularly, it just completely destroys the game. After losing most of their good treasures, they're going to have to constantly trash their actions and victory cards, eventually leaving them unable to do anything, because Conflagration is completely ludicrous in its effect. The fact it costs debt also means you can get them easily, so if your opponent does anything to leave themselves vulnerable - such as the basic act of thinning out coppers, he's going to end up having a completely miserable game.
On top of that, there's the whole rules issue Conflagration's trashing rule causes. You almost always don't want to say something "cannot" be done, because it can create a ton of issues. I think the only cards that have that wording currently are things restricting buys (Grand Market and Contraband). But in this case, say I look at one with Lookout. What happens if I choose it as my card to trash? Or can I just not do that? What if I look at three of them? Now what happens when resolving Lookout? Either I have to trash one, or Lookout ends up with a card sitting in look at limbo. You almost certainly want some kind of on trash penalty instead, rather than outright banning trashing it. On top of that, its effect is far too broad, random and powerful. A card that can just randomly force players to sometimes trash a Province with no recourse, and other times just an Estate is not good. On top of that, with several Dragons you could easily fill an opponents deck with these, and unless they have a really insane engine, that's basically game over, because everything that isn't money is gonna disappear - and they probably don't have much money left because they were pushing back the Conflagrations for so long.
I would look at narrowing down the effects the card can have, so it isn't quite so broad. Pirate Ship and Torturer are probably good cards to look at for inspiration of what you could do. For example, Dragon could force players to trash a treasure from their hand, and then put one of the trashed cards onto the mat, in a manner similar to Pirate Ship tokens (alternatively, it could just collect tokens, like Pirate Ship does - or just give money if any treasure was trashed in this way with no building up or recording the treasure, which simplifies things a lot. Conflation needs a lot of changes. It could still be some kind of on-draw penalty, but make it much weaker. You're already using Debt, so how about taking 1 debt? That's probably still too much since you could get bogged down pretty heavily, so... maybe something like if you have 2 or less debt, take 1 debt. You could also make it have an on-trash penalty to take more debt (1-2 more probably). That way taking a Conflation or two isn't going to totally ruin the rest of your game - it's gonna hurt, especially if you can't trash it, but it'll be a lot more balanced.