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Combo: Apothecary/Vault
Fangz:
The real problem, as I see it, is acquiring those apothecaries without disrupting the rest of your game. If you can pick up a decent amount from time to time, sure, they are a help, but with vault guaranteeing you a gold, when choosing between an apothecary and a gold I'd usually opt for a gold (or a vault).
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