I see Apothecary+Alchemist as really powerful non-terminal drawing. Maybe add Menagerie later for support, especially add at least 1 for Fairgrounds. You should be able to deploy all 10 Curses quite fast. This will slow down the Rebuild player just a bit, but more importantly, it is +10 VP for you. If you get going fast, you can deny a couple of Duchies (keeping one for Fairgrounds) thus stopping the Rebuild player to end the game as fast (they will need to buy out Estates probably). With 6 VP Fairgrounds, you should beat a Rebuild player that cannot amass more than maybe 6 Provinces.
I agree with the general sense that Rebuild is incredibly easy to play and the engine is a tough one, so it is much easier for the engine player to make a game losing mistake. You need to track your discard and the score pretty well.