First, thanks for the simulator. It's very helpful.
I saw the the question on your site for suggestions on how to optimize play rules. I say don't optimize them, let us choose them.
I don't see much choice if you want to keep going further with the simulator. I'm guessing you've already thought of it. Break it into the three game phases; Action Rules, Buy Rules, and Cleanup Rules. But obviously that's where it gets tough. There are so many choices that could come up.
Action rules could be just like the buy rules.
Play XXXXX
Play condition if XXXXXX
Play choices XXXXXX
Buy phase could also use play rules for things like Loan, HoP, Ill-Gotten.
Cleanup play rules would be pretty limited, mostly for cards with top-decking options.
Then the simulator would be a full strategy simulator where we can tweak with the best way to play cards. I don't know if that's where you want to go with it, or if you have the time to do it. I know I certainly don't have the spare time to create something like that. So I thank you the work you have done. Even as is, the simulator is an amazing tool.