Sklansky's FTOP is misleading anyway. The reason is because you can never know your opponent's exact hand (barring some sort of ridiculous tell). What you actually know is your opponent's RANGE of hands. You CANNOT play optimally against his exact hand. You can only play optimally against his range of hands.
Suppose you know for certain that your opponent will go all-in preflop only with AA and AK. Given his range (and a rakeless environment), it is always mathematically correct to call him with 22 because there are only 6 ways he can make AA, and 16 ways he can make AK(of course you may pass up on this slight edge if you know you are a much better player than him and may get a better edge in the future). FTOP says if you knew he had AA, you would fold, and if you knew he had AK you would call. But again, you CAN'T know that information.
Applying this proper understanding to Dominion, we can actually use it to help us make meaningful decisions. Suppose you have been counting your opponents cards and your own. You are considering breaking the PPR as there are 2 provinces left, and if you get both you know you will win. However, you will lose if he can buy the last 1 on his turn. Suppose you have 8 this turn, and given your deck composition you know you will have 8 next turn. He has 10 cards left in his deck, consisting of Gold, Gold, Estate, Province, Silver, Silver, Curse, Curse, Province, Province. Do you break the PPR?
All that must be done is that you must analyze your opponent's RANGE of possible hands. How many ways can he make 8? Only 2 ways, with both Golds and one of the silvers, or both Golds and the other silver (obviously he can make more than 8 by adding to these combinations, but that is what he needs at minimum). Compare this to the many combinations of 3 cards that will NOT make 8. Clearly, here you SHOULD break the PPR.
Now, if your opponent proceeds to buy the last province on his turn, did you play incorrectly? Absolutely not. You made the best possible play against his RANGE, and it is mathematically correct every time regardless of what actually happens.
This example may seem rather contrived, but it illustrates the point. And rather than keeping track of exact information like that, you can easily keep rough track of your opponent's deck composition. Has he already seen his ONLY Gold this shuffle? That can inform your future decisions. Did he already play both his tournaments this shuffle without revealing either of his provinces? That can inform your future decisions. Hope this was helpful.