A little variation on DStu's solution to score 88 points with a single click.
Our overall objective is to get 10 Highways in play, then play 4 Remakes on 8 Curses to transform them to Colonies. To get this to work, we'll need 5 Throne Roomed Golems. So that's a total of 19 non-Golem actions, one of which is played by us and the rest needing 18/4 = 4.5 of the TR'd Golems. That means we'll have two spare Golem actions, so we can fill that with some other action; I'll choose Moneylender in order to counteract the over-drawing of the Highways (since we only want the 8 Curses in hand once the Remakes are hit).
Here's how it goes specifically: our initial hand is TR, Golem, Golem, Golem, Copper.
TR
- Golem 1.1 (find 2 Moneylenders) => clears out the Copper from our hand (now hand is two Golems)
- Golem 1.2 (find 2 TR)
-- TR
--- Golem 2.1 (find 2 Highways) => draws Golem, Golem (now hand is three Golems)
--- Golem 2.2 (find 2 TR)
---- TR
----- Golem 3.1 (find 2 Highways) => draws Curse, Curse
----- Golem 3.2 (find 2 Highways) => draws Curse, Curse (now hand is 2 Golems, 4 Curses)
---- TR
----- Golem 4.1 (find 2 Highways) => draws Curse, Curse
----- Golem 4.2 (find 2 Highways) => draws Curse, Curse (now hand is 1 Golem, 8 Curses)
-- TR
--- Golem 5.1 (find 2 Remakes) => 4 Curses become Colonies
--- Golem 5.2 (find 2 Remakes) => 4 Curses become Colonies