I've only just felt like I got a handle on some Adventures cards. I have no idea what I'm doing with Empires.
Most Events are pretty impactful. Both the Page and Peasant line are very dominant and until you know better it's best to assume you should always be opening 1 Page or 1 Peasant.
Masquerade pins are dead, which is good because Royal Carriage-Masquerade was a 2 card combo for pinning.
Distant Lands are deceptively strong. I'm not sure what the right timing is, but you buy Distant Lands over Gold very quickly in BM, and almost always want to pick some up in engine games, unless you need the points right now to avoid losing to 3 piles. 4 VP out of your deck is very useful, and because they're an action you can sometimes gain them faster than you'd expect (University, Procession, etc.).
Artificer topdecks the card you gain. I almost always forget this when playing with the card. The only reason I remember Artificer topdecks is because I remember that I always forget it topdecks cards. Funny how that works.