1. worker's village + lookout is not a terrible opening with peddlers lurking, especially because you'll want the worker's village later for torturing. wv + silver makes a little less sense to me, but isn't terrible. i may be wrong, as the power fives are so important that it may be worth foregoing an aggressive peddler opening in favor of making sure you'll get 5 on the second shuffle. but wv + silver seems like a mix and match of an aggressive peddler opening and a make sure you get 5 on the second shuffle opening, and that can't be right. lookout + lookout is not bad at scoring you peddlers either.
2. fundamentally, i think ghost ship is a distraction in this game. OK, playing a ghost ship and then a bunch of torturers is really mean, but playing a bunch of torturers is
a. less mean, but still really really mean
b. a lot easier to pull off, since
i. the torturer draws you more cards, making a turn where you fire off that much more likely and
ii. if your chain of meanness depends only on four torturers, then it doesn't matter which one's on top. but if it invovles ghost ship, the ghost ship has to be in your hand - with a village, of course - for the chain to work. That's asking for too much luck, at least without something like scheme around. GS + torturer + torturer + torturer is infinitesimally meaner than quadruple torturer, but torturer + torturer + GS + torturer is nicer! (and nets you fewer cards.)
(edit: 2.b.ii is probably true, but not as clear as I make it sound. ghost ship in the middle of a torturer chain is meaner than another torturer if your opponent has been taking curses; it's only nicer if the opponent has 3 or fewer cards in hand. i stand by the gist of the argument, which is that the mean-ness is luck-dependent.)