Planning to update this with the new 2nd Edition sets at some point. I haven't finished going through them all, but so far it looks like any of the sets involving a non-Base/Intrigue expansion are the same except for the cards which have been replaced. However, the Base only, Intrigue only, and Base/Intrigue sets are very different (except for First Game, which only had Woodcutter -> Merchant); some have the same name but different cards, some have new names.
Base:
First Game (Woodcutter -> Merchant)
Size Distortion (6 changes)
Big Money, Interaction, Village Square -> Deck Top, Sleight of Hand, Improvements, Silver & Gold
Intrigue:
Victory Dance (5 changes)
Best Wishes (5 changes)
Secret Schemes -> The Plot Thickens
Intrigue/Base:
Deconstruction (7 changes)
Underlings (4 changes)
Hand Madness -> Grand Scheme
Seaside/Base:
Reach for Tomorrow (Spy, Adventurer -> Artisan, Vassal)
Repetition (Chancellor -> Harbinger)
Give and Take (None)
Seaside/Intrigue:
(All New) A Star to Steer By, Shore Patrol, Bridge Crossing
Alchemy/Base:
Forbidden Arts (Thief -> Bandit)
Potion Mixers (Chancellor -> Poacher)
Chemistry Lesson (Woodcutter -> Vassal)
Alchemy/Intrigue:
Servants (Great Hall -> Mill)
Secret Research (None)
Pools, Tools, and Fools (Coppersmith -> Lurker)
Prosperity/Base:
Biggest Money (Adventurer, Spy -> Artisan, Harbinger)
The King's Army (Spy -> Merchant)
The Good Life (Chancellor -> Artisan)
Prosperity/Intrigue:
Paths to Victory (None)
All Along the Watchtower (Great Hall -> Mill)
Lucky Seven (Coppersmith, Tribute -> Lurker, Patrol)
Cornucopia/Base:
Bounty of the Hunt (None)
Bad Omens (Adventurer, Spy -> Merchant, Poacher)
The Jester's Workshop (Feast, Chancellor -> Artisan, Merchant)
Cornucopia/Intrigue:
Last Laughs (None)
The Spice of Life (Coppersmith, Great Hall, Tribute -> Courtier, Diplomat, Replace)
Small Victories (Great Hall -> Secret Passage)
Hinterlands/Base:
Highway Robbery (None)
Adventures Abroad (Adventurer, Chancellor -> Sentry, Vassal)
Hinterlands/Intrigue:
Money for Nothing (Coppersmith, Great Hall -> Patrol, Replace)
The Duke's Ball (None)
Dark Ages/Base:
High and Low (None)
Chivalry and Revelry (None)
Dark Ages/Intrigue:
Prophecy (Great Hall -> Secret Passage)
Invasion (Mining Village -> Diplomat)
Guilds/Base:
Arts and Crafts (None)
Clean Living (Thief -> Bandit)
Gilding the Lily (Adventurer, Chancellor -> Merchant, Sentry)
Guilds/Intrigue:
Name That Card (Tribute -> Replace)
Tricks of the Trade (Coppersmith, Great Hall -> Mill, Secret Passage)
Decisions, Decisions (None)
Adventures/Base:
Level Up (Spy -> Merchant)
Son of Size Distortion (Thief -> Bandit)
Adventures/Intrigue:
Royalty Factory (Secret Chamber -> Courtier)
Masters of Finance (None)
Empires/Base:
Everything in Moderation (None)
Silver Bullets (None)
Empires/Intrigue:
Delicious Torture (None)
Buddy System (None)