I was looking at Prismata on Steam for a while, and I finally got it while it was free. So far, I've only played the episode 1 campaign, and some of the other single-player content. I'm not sure I'm really interested in playing against randos, but I told a couple friends to get it too, so maybe I'll play with them at some point. Here are some impressions so far.
Compared to Dominion, this seems far more optimized for digital/online play. It's relatively easy to visually parse. There aren't any mechanics like shuffling, which I think is far easier to track and understand when you're doing the shuffling physically. It's designed for timed play, which solves the slow-rolling problem. And it seems much more amenable to AI.
I couple things I'm less fond of: It's very math-y. And I tend to prefer games that are about parallel building up, rather than direct confrontation.
I don't have a great understanding of the strategy, but this morning I had the realization that it's sort of like Temporum, where everything has a "par" value. In Temporum the expected value of a turn is $8, with cards = crowns = $4, but you might make more or less depending on tactics. In Prismata, there's a "par" interest rate of 33% a turn, so that 3 of anything this turn is worth 4 next turn. We also have Gaussite ~ Replicase ~ $1, Behemium ~ $2, and a single point of damage/defense is worth a bit more than $2. I tried calculating the values of a few basic units, and it seems that Gauss Cannons are about par, Tarsiers are above par, Walls are only better than par if they absorb damage. Rhinos just seem weak...